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UNL scientists discover key mutations in cattle

UNL scientists discover key mutations in cattle


By Scout Nelson

Researchers at the University of Nebraska-Lincoln have made significant advances in livestock genetics by identifying two new genetic mutations in cattle. These discoveries, which involve delayed blindness in Herefords and bovine familial convulsions and ataxia in Angus cattle, will aid beef producers in making informed breeding decisions.

The research team, after years of genomic studies, developed tests to help producers avoid breeding cattle that may carry these harmful mutations. The identification of these conditions was possible thanks to the collaboration between cattle producers, breed associations, and the university.

One of the conditions, delayed blindness, affects Hereford cattle and stems from a recessive mutation in a gene related to a similar condition in humans known as juvenile neuronal ceroid lipofuscinoses.

This mutation causes progressive blindness and was traced back to a common ancestor among affected animals. A commercial genetic test is now available, helping producers manage this mutation in their herds.

In Angus cattle, a dominant mutation causing bovine familial convulsions and ataxia was discovered. This condition, which leads to seizures and poor calf vitality, was found in a single herd and traced to one founder animal. This mutation illustrates how dominant genetic conditions can be more immediately noticeable than recessive ones, allowing for quicker management decisions.

The collaboration between University of Nebraska-Lincoln researchers, the American Hereford Association, and experts like Tom Hairgrove from Texas A&M University and Jon Beever from the University of Tennessee was pivotal in these discoveries.

Their efforts highlight the importance of reporting health issues to breed associations, which can initiate investigations into potential genetic causes.

These genetic findings are critical for the ongoing improvement of cattle breeds and herd health. By understanding and managing these conditions, producers can ensure the vitality and productivity of their livestock. The role of genetics in animal health continues to provide valuable insights that drive the agricultural industry forward.

Photo Credit: gettyimages-pamwalker68

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Categories: Nebraska, Livestock, Beef Cattle

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